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Article

Association between genetic polymorphisms in chromosome region 9q21 and pelvic organ prolapse in Northwestern Chinese women.

African journal of reproductive health - 30 Sept 2024

Wang Jian, Wei Ying, Mao Baohong, Xu Wenjing, Liu Xiyun, Tao Chengbing, Lu Yongli, Sheng Yannan, Liu Qing

Abstract excerpt

This study aimed to explore the association between genetic polymorphisms in the chromosome region 9q21 and the risk of pelvic organ prolapse (POP) in Northwestern Chinese women. A case-control study was conducted with 241 POP patients and 268 healthy controls, analyzing ten single nucleotide polymorphisms (SNPs) across five genes using PCR amplification and Sequenom MassArray. The results revealed significant...

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PMID: 39373292
DOI: 10.29063/ajrh2024/v28i9.17

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