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Article

RAB40C gene polymorphisms rs62030917 and rs2269556 are associated with an increased risk of lumbar disc herniation development in the Chinese Han population.

The journal of gene medicine - 1 Apr 2021

Liu Kexun, Huo Hongjun, Jia Wenchao, Li Manglai, Xiong Zichao, Sun Yao, Wu Jiamin, Li Haiyue, Liu Jianfeng, Liu Yuanwei, Jin Tianbo, Li Bin, Zuo Yuan, Zhao Yan

Abstract excerpt

BACKGROUND: Lumbar disc herniation (LDH) places a serious burden on the daily lives and socioeconomics of people. Although the pathogenesis of LDH is complex, genetic factors such as single nucleotide polymorphisms (SNPs) may affect the risk of developing LDH. In the present study, we aimed to elucidate the effect of RAB40C SNPs on the risk of LDH in the Chinese Han population. METHODS: We investigated 508 LDH...

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PMID: 32656896
DOI: 10.1002/jgm.3252

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