Article
Is laminin gamma-1 a candidate gene for advanced pelvic organ prolapse?
American journal of obstetrics and gynecology - 1 May 2010
Chen Chen, Hill Lori D, Schubert Christine M, Strauss Jerome F, Matthews Catherine A
Abstract excerpt
OBJECTIVE: We sought to determine allele frequencies of 3 LAMC1 single nucleotide polymorphisms (SNPs) in Caucasian and African American (AA) women with stage>II pelvic organ prolapse (POP) (cases) and in ethnicity-matched controls with stage<II POP. We also sought to determine if LAMC1 is associated with POP within ethnic groups. STUDY DESIGN: Allelic discrimination was performed for LAMC1 SNPs rs10911193 (C/T),...
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