Article
Genetic polymorphisms in collagen-related genes are associated with pelvic organ prolapse.
Menopause (New York, N.Y.) - 1 Feb 2020
Li Lei, Sun Zhijing, Chen Juan, Zhang Ye, Shi Honghui, Zhu Lan
Abstract excerpt
OBJECTIVE: Pelvic organ prolapse (POP) is a common health issue that has a profound negative influence on women's quality of life. Genetic susceptibility to POP has been increasingly investigated. In this study, we assessed the single-nucleotide polymorphisms (SNPs) of six collagen-related genes (COL14A1, COL5A1, COL4A2, COL3A1, COL1A1, and COL18A1) and the genetic association with POP in Chinese women. METHODS:...
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