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Article

A functional polymorphism located at transcription factor binding sites, rs6695837 near LAMC1 gene, confers risk of colorectal cancer in Chinese populations.

Carcinogenesis - 1 Feb 2017

Lou Jiao, Gong Jing, Ke Juntao, Tian Jianbo, Zhang Yi, Li Jiaoyuan, Yang Yang, Zhu Ying, Gong Yajie, Li Lu, Chang Jiang, Zhong Rong, Miao Xiaoping

Abstract excerpt

Genome-wide association studies (GWASs) have identified multiple single nucleotide polymorphisms (SNPs) associated with colorectal cancer (CRC) susceptibility. However, the elucidation of causal SNPs and the biological mechanisms behind are still limited. In this study, we initially performed systematic bioinformatics analyses on CRC GWAS-identified loci to seek for potential functional SNPs located at...

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PMID: 28039327
DOI: 10.1093/carcin/bgw204

Genes

LAMC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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