Article

A novel missense variant of LAMC1 as a possible cause of premature ovarian insufficiency in a Chinese family

2022-02-23

Abstract excerpt

<h4>Background: </h4> Premature ovarian insufficiency (POI) results in the loss of ovarian function and reproductive impairment. The cause of most cases of POI is unclear, although genetic factors are thought to be involved. This study aimed to identify novel pathogenic genes and variants in a Chinese family with POI. <h4>Results: </h4>: An assessment of the family pedigree suggested that POI was inherited in an a...

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Literature Corpus work: 2b22f023-355c-5f9b-a2dd-55cb57ad4409
DOI: 10.21203/rs.3.rs-1375481/v1

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