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Article

Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse.

American journal of obstetrics and gynecology - 1 May 2012

Wu Jennifer M, Visco Anthony G, Grass Elizabeth A, Craig Damian M, Fulton Rebekah G, Haynes Carol, Amundsen Cindy L, Shah Svati H

Abstract excerpt

OBJECTIVE: We sought to comprehensively evaluate the association of laminin gamma-1 (LAMC1) and advance pelvic organ prolapse. STUDY DESIGN: We conducted a candidate gene association of patients (n = 239) with stages III-IV prolapse and controls (n = 197) with stages 0-I prolapse. We used a linkage disequilibrium (LD)-tagged approach to identify single-nucleotide polymorphisms (SNPs) in LAMC1 and focused on...

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Source

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Identifiers

PMID: 22342894
DOI: 10.1016/j.ajog.2012.01.033
PMCID: PMC3508006

Genes

LAMC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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