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Article

Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment.

Nucleic acids research - 20 Aug 2020

Nechooshtan Gal, Yunusov Dinar, Chang Kenneth, Gingeras Thomas R

Abstract excerpt

Extracellular RNAs participate in intercellular communication, and are being studied as promising minimally invasive diagnostic markers. Several studies in recent years showed that tRNA halves and distinct Y RNA fragments are abundant in the extracellular space, including in biofluids. While their regulatory and diagnostic potential has gained a substantial amount of attention, the biogenesis of these...

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PMID: 32609822
DOI: 10.1093/nar/gkaa526
PMCID: PMC7430647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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