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Article

Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction.

Circulation. Genomic and precision medicine - 1 Aug 2020

Choquet Hélène, Thai Khanh K, Jiang Chen, Ranatunga Dilrini K, Hoffmann Thomas J, Go Alan S, Lindsay Alistair C, Ehm Margaret G, Waterworth Dawn M, Risch Neil, Schaefer Catherine

Abstract excerpt

BACKGROUND: Left ventricular ejection fraction (EF) is an indicator of cardiac function, usually assessed in individuals with heart failure and other cardiac conditions. Although family studies indicate that EF has an important genetic component with heritability estimates up to 0.61, to date only 6 EF-associated loci have been reported. METHODS: Here, we conducted a genome-wide association study (GWAS) of EF in...

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Identifiers

PMID: 32605384
DOI: 10.1161/CIRCGEN.119.002804
PMCID: PMC7446727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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