Article
The ABO Locus is Associated with Increased Fibrin Network Formation in Patients with Stable Coronary Artery Disease.
Thrombosis and haemostasis - 1 Sept 2020
Winther-Larsen Anne, Christiansen Morten Krogh, Larsen Sanne Bøjet, Nyegaard Mette, Neergaard-Petersen Søs, Ajjan Ramzi A, Würtz Morten, Grove Erik Lerkevang, Jensen Henrik Kjærulf, Kristensen Steen Dalby, Hvas Anne-Mette
Abstract excerpt
BACKGROUND: The ABO locus has been associated with increased risk of myocardial infarction (MI) in patients with coronary artery disease (CAD), but the underlying mechanisms are unknown. As altered fibrin clot structure has been demonstrated to predict MI in CAD patients, we examined the association between the ABO risk variant and fibrin clot properties, and investigated the effects of other CAD-associated risk...
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