Article
Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction.
American heart journal - 1 Dec 2007
Knowles Joshua W, Wang Huijan, Itakura Haruka, Southwick Audrey, Myers Richard M, Iribarren Carlos, Fortmann Stephen P, Go Alan S, Quertermous Thomas, Hlatky Mark A
Abstract excerpt
BACKGROUND: Genetic polymorphisms may affect the balance between coagulation and fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) among patients with underlying coronary atherosclerosis. METHODS: We enrolled 1375 patients with an initial clinical presentation of coronary disease. We genotyped 49 single nucleotide polymorphisms (SNPs) in 9 coagulation system genes and...
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