Article
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
Annals of neurology - 1 Jan 2013
Williams Frances M K, Carter Angela M, Hysi Pirro G, Surdulescu Gabriela, Hodgkiss Dylan, Soranzo Nicole, Traylor Matthew, Bevan Steve, Dichgans Martin, Rothwell Peter M W, Sudlow Cathie, Farrall Martin, Silander Kaisa, Kaunisto Mari, Wagner Peter, Saarela Olli, Kuulasmaa Kari, Virtamo Jarmo, Salomaa Veikko, Amouyel Philippe, Arveiler Dominique, Ferrieres Jean, Wiklund Per-Gunnar, Ikram M Arfan, Hofman Albert, Boncoraglio Giorgio B, Parati Eugenio A, Helgadottir Anna, Gretarsdottir Solveig, Thorsteinsdottir Unnur, Thorleifsson Gudmar, Stefansson Kari, Seshadri Sudha, DeStefano Anita, Gschwendtner Andreas, Psaty Bruce, Longstreth Will, Mitchell Braxton D, Cheng Yu-Ching, Clarke Robert, Ferrario Marco, Bis Joshua C, Levi Christopher, Attia John, Holliday Elizabeth G, Scott Rodney J, Fornage Myriam, Sharma Pankaj, Furie Karen L, Rosand Jonathan, Nalls Mike, Meschia James, Mosely Thomas H, Evans Alun, Palotie Aarno, Markus Hugh S, Grant Peter J, Spector Tim D
Abstract excerpt
OBJECTIVE: End-stage coagulation and the structure/function of fibrin are implicated in the pathogenesis of ischemic stroke. We explored whether genetic variants associated with end-stage coagulation in healthy volunteers account for the genetic predisposition to ischemic stroke and examined their influence on stroke subtype. METHODS: Common genetic variants identified through genome-wide association studies of...
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