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Article

Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.

Proceedings of the National Academy of Sciences of the United States of America - 14 Jul 2020

Nguyen Ha An, Sunita S, Dunham Christine M

Abstract excerpt

Bacterial transfer RNAs (tRNAs) contain evolutionarily conserved sequences and modifications that ensure uniform binding to the ribosome and optimal translational accuracy despite differences in their aminoacyl attachments and anticodon nucleotide sequences. In the tRNA anticodon stem-loop, the anticodon sequence is correlated with a base pair in the anticodon loop (nucleotides 32 and 38) to tune the binding of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32601241
DOI: 10.1073/pnas.2004170117
PMCID: PMC7368331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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