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Article

Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71.

Viruses - 17 Jun 2020

Mandary Madiiha Bibi, Masomian Malihe, Ong Seng-Kai, Poh Chit Laa

Abstract excerpt

Viral plaque morphologies in human cell lines are markers for growth capability and they have been used to assess the viral fitness and selection of attenuated mutants for live-attenuated vaccine development. In this study, we investigate whether the naturally occurring plaque size variation reflects the virulence of the variants of EV-A71. Variants of two different plaque sizes (big and small) from EV-A71...

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Identifiers

PMID: 32560288
DOI: 10.3390/v12060651
PMCID: PMC7354493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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