Article
Changes in mumps virus neurovirulence phenotype associated with quasispecies heterogeneity.
Virology - 20 Jun 2006
Sauder Christian J, Vandenburgh Kari M, Iskow Rebecca C, Malik Tahir, Carbone Kathryn M, Rubin Steven A
Abstract excerpt
Mumps virus is a highly neurotropic virus with evidence of central nervous system invasion (CNS) in approximately half of all cases of infection. In countries where live attenuated mumps virus vaccines were introduced, the number of mumps cases declined dramatically; however, recently, the safety of some vaccine strains has been questioned. For example, one of the most widely used vaccines, the Urabe AM9 strain,...
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