Article
Angiogenesis-Centered Molecular Cross-Talk in Amyotrophic Lateral Sclerosis Survival: Mechanistic Insights.
Critical reviews in eukaryotic gene expression - 1 Jan 2020
Thakur Keshav, Tiwari Abha, Sharma Kaushal, Modgil Shweta, Khosla Radhika, Anand Akshay
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized with progressive muscle atrophy. We have attempted to establish the link between angiogenesis and cellular survival in the pathogenesis of ALS by compiling evidence described in various scientific reports. The phenotypes of human ALS have earlier been captured in the mutant SOD1 mice as well as by targeted deletion of the...
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