Article
Another angiogenic gene linked to amyotrophic lateral sclerosis.
Trends in molecular medicine - 1 Aug 2006
Lambrechts Diether, Lafuste Peggy, Carmeliet Peter, Conway Edward M
Abstract excerpt
A new study by Greenway and colleagues links mutations in the angiogenin gene to patients with amyotrophic lateral sclerosis (ALS)--a progressive and fatal motoneuron disease. This is an unexpected finding because angiogenin was originally identified as a molecule involved in the formation of blood vessels (angiogenesis). Angiogenin bears striking similarity to vascular endothelial growth factor (VEGF), which is...
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