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Article

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

Annals of neurology - 1 Oct 2004

Zheng Chengyun, Nennesmo Inger, Fadeel Bengt, Henter Jan-Inge

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with the death of motor neurons in the spinal cord and brainstem. The cause of ALS is unknown and there is no cure. This study demonstrates, for the first time, that vascular endothelial growth factor (VEGF) delays progression of symptoms and prolongs survival in a Cu/Zn superoxide dismutase (SOD1) transgenic mouse model of ALS....

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Source

Identifiers

PMID: 15389897
DOI: 10.1002/ana.20223

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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