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Article

Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis.

The Journal of cell biology - 7 Sept 2020

Panda Pallavi, Kovacs Levente, Dzhindzhev Nikola, Fatalska Agnieszka, Persico Veronica, Geymonat Marco, Riparbelli Maria Giovanna, Callaini Giuliano, Glover David M

Abstract excerpt

Rcd4 is a poorly characterized Drosophila centriole component whose mammalian counterpart, PPP1R35, is suggested to function in centriole elongation and conversion to centrosomes. Here, we show that rcd4 mutants exhibit fewer centrioles, aberrant mitoses, and reduced basal bodies in sensory organs. Rcd4 interacts with the C-terminal part of Ana3, which loads onto the procentriole during interphase, ahead of Rcd4...

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Identifiers

PMID: 32543652
DOI: 10.1083/jcb.201912154
PMCID: PMC7401805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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