Article
The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis.
The Journal of cell biology - 7 Jun 2004
Martinez-Campos Maruxa, Basto Renata, Baker James, Kernan Maurice, Raff Jordan W
Abstract excerpt
Centrosomes consist of a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Proteins that contain a Pericentrin/AKAP450 centrosomal targeting (PACT) domain have been implicated in recruiting several proteins to the PCM. We show that the only PACT domain protein in Drosophila (the Drosophila pericentrin-like protein [D-PLP]) is associated with both the centrioles and the PCM, and is...
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