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Article

Plk4 regulates centriole duplication in the embryonic development of zebrafish.

Developmental biology - 1 Jan 2025

Mu Zhiyu, Zheng Pengfei, Liu Shuangyu, Kang Yunsi, Xie Haibo

Abstract excerpt

PLK4 plays a crucial role in centriole duplication, which is essential for maintaining cellular processes such as cell division, cytoskeletal stability, and cilia formation. However, the mechanisms of PLK4 remain incompletely understood, especially in the embryonic development of vertebrate species. In this study, we observed that Plk4 dysfunction led to abnormal embryonic development in zebrafish, characterized...

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Identifiers

PMID: 39304174
DOI: 10.1016/j.ydbio.2024.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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