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Article

9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures.

Nature communications - 25 May 2024

Panda Pallavi, Ladinsky Mark S, Glover David M

Abstract excerpt

As daughter centrioles assemble during G2, they recruit conserved Ana3/RTTN followed by its partner Rcd4/PPP1R35. Together, this contributes to the subsequent recruitment of Ana1/CEP295, required for the centriole's conversion to a centrosome. Here, we show that Rcd4/PPP1R35 is also required to maintain 9-fold centriole symmetry in the Drosophila male germline; its absence causes microtubule triplets to disperse...

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Source

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Identifiers

PMID: 38796459
DOI: 10.1038/s41467-024-48831-y
PMCID: PMC11127918

Genes

CEP295
RTTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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