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Article

Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control.

Molecular biology of the cell - 1 Feb 2009

Keller Lani C, Geimer Stefan, Romijn Edwin, Yates John, Zamora Ivan, Marshall Wallace F

Abstract excerpt

Centrioles are intriguing cylindrical organelles composed of triplet microtubules. Proteomic data suggest that a large number of proteins besides tubulin are necessary for the formation and maintenance of a centriole's complex structure. Expansion of the preexisting centriole proteome from the green alga Chlamydomonas reinhardtii revealed additional human disease genes, emphasizing the significance of centrioles...

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Source

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Identifiers

PMID: 19109428
DOI: 10.1091/mbc.e08-06-0619
PMCID: PMC2642750

Genes

AHI1
MKS1
NPHP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control.PMID 19109428Read ↗

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