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Article

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1

16 Jun 2020

Abstract excerpt

Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a nonselective cation channel permeable to Ca2+ that belongs to the family of transient receptor potential channels, is required for autophagy in multiple cell types by a mechanism that remains...

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PMID: 32543276
DOI: 10.1080/15548627.2020.1782035

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