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Article

A Change in Domain Cooperativity Drives the Function of Calnuc.

Biochemistry - 14 Jul 2020

Vignesh Ravichandran, Aradhyam Gopala Krishna

Abstract excerpt

With the increasing incidence of neurodegenerative disorders, there is an urgent need to understand the protein folding process. Examining the folding process of multidomain proteins remains a prime challenge, as their complex conformational dynamics make them highly susceptible to misfolding and/or aggregation. The presence of multiple domains in a protein can lead to interaction between the partially folded...

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PMID: 32543177
DOI: 10.1021/acs.biochem.0c00207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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