Association between Fetal MTHFR A1298C (rs1801131) Polymorphism and Neural Tube Defects Risk: A Systematic Review and Meta-Analysis.

doi:10.1080/15513815.2020.1764682

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Article

Association between Fetal MTHFR A1298C (rs1801131) Polymorphism and Neural Tube Defects Risk: A Systematic Review and Meta-Analysis.

Fetal and pediatric pathology - 1 Feb 2022

Soleimani-Jadidi Sara, Meibodi Bahare, Javaheri Atiyeh, Tabatabaei Razieh Sadat, Hadadan Amaneh, Zanbagh Leila, Abbasi Hajar, Bahrami Reza, Mirjalili Seyed Reza, Karimi-Zarchi Mojgan, Neamatzadeh Hossein

Abstract excerpt

BACKGROUND: The association of the fetal MTHFR A1298C (rs1801131) polymorphism and neural tube defects (NTDs) susceptibility has been widely demonstrated, but the results remain inconclusive. Thus, we performed a meta-analysis to investigate the association between fetal MTHFR A1298C polymorphism and NTDs risk. METHODS: An electronic search of PubMed, web of science, SciELO, CNKI database for studies on the fetal...

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PMID: 32536231
DOI: 10.1080/15513815.2020.1764682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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