Article
Neural-specific distribution of transmembrane protein TMEM240 and formation of TMEM240-Body.
International journal of biological macromolecules - 15 Oct 2020
Hu Qiongqiong, Wang Guangyou, Chen Xin, Zhang Liulei, Zhao Wei, Jiang Yan, Zhang Chong, Sun Jin, Xu Hao, Li Hulun, Kong Qingfei, Zhao Jiarui, Li Xinrong, Zhang Xiaoyu, Lv Weiqi, Liu Yumei, Yang Gaiqing, Mu Lili, Wang Jinghua
Abstract excerpt
Mutation in TMEM240 is suggested to cause SCA21, but the specific mechanism has not been clarified. The subcellular localization, specific biological function, and corresponding mechanism of action of TMEM240 have also not been delineated. In this study, the mRNA and protein expression of TMEM240 were assessed using qPCR and western blotting, respectively. Live cell imaging was used to establish the sub-cellular...
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