Article
Controversy of TMEM230 Associated with Parkinson's Disease.
Neuroscience - 15 Jan 2021
Wang Xiaobo, Whelan Emma, Liu Zhaohui, Liu Chun-Feng, Smith Wanli W
Abstract excerpt
Parkinson's disease (PD) is a common neurodegenerative disease with movement disorders including resting tremor, bradykinesia, rigidity, and postural instability. The key pathological features of PD are selective loss of dopaminergic (DA) neurons in substantial nigra and the presence of Lewy bodies (LBs). Mutations in TMEM230 (transmembrane protein 230) have been recently reported to play a pathological role and...
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