Article
Identification of TMEM230 mutations in familial Parkinson's disease.
Nature genetics - 1 Jul 2016
Deng Han-Xiang, Shi Yong, Yang Yi, Ahmeti Kreshnik B, Miller Nimrod, Huang Cao, Cheng Lijun, Zhai Hong, Deng Sheng, Nuytemans Karen, Corbett Nicola J, Kim Myung Jong, Deng Hao, Tang Beisha, Yang Ziquang, Xu Yanming, Chan Piu, Huang Bo, Gao Xiao-Ping, Song Zhi, Liu Zhenhua, Fecto Faisal, Siddique Nailah, Foroud Tatiana, Jankovic Joseph, Ghetti Bernardino, Nicholson Daniel A, Krainc Dimitri, Melen Onur, Vance Jeffery M, Pericak-Vance Margaret A, Ma Yong-Chao, Rajput Ali H, Siddique Teepu
Abstract excerpt
Parkinson's disease is the second most common neurodegenerative disorder without effective treatment. It is generally sporadic with unknown etiology. However, genetic studies of rare familial forms have led to the identification of mutations in several genes, which are linked to typical Parkinson's disease or parkinsonian disorders. The pathogenesis of Parkinson's disease remains largely elusive. Here we report a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.