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Article

The TMEM240 Protein, Mutated in SCA21, Is Expressed in Purkinje Cells and Synaptic Terminals.

Cerebellum (London, England) - 1 Jun 2020

Homa Mégane, Loyens Anne, Eddarkaoui Sabiha, Faivre Emilie, Deramecourt Vincent, Maurage Claude-Alain, Buée Luc, Huin Vincent, Sablonnière Bernard

Abstract excerpt

A variety of missense mutations and a stop mutation in the gene coding for transmembrane protein 240 (TMEM240) have been reported to be the causative mutations of spinocerebellar ataxia 21 (SCA21). We aimed to investigate the expression of TMEM240 protein in mouse brain at the tissue, cellular, and subcellular levels. Immunofluorescence labeling showed TMEM240 to be expressed in various areas of the brain, with...

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Identifiers

PMID: 32002801
DOI: 10.1007/s12311-020-01112-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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