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Article

Sub-nanowatt resolution direct calorimetry for probing real-time metabolic activity of individual C. elegans worms.

Nature communications - 12 Jun 2020

Hur Sunghoon, Mittapally Rohith, Yadlapalli Swathi, Reddy Pramod, Meyhofer Edgar

Abstract excerpt

Calorimetry has been widely used in metabolic studies, but direct measurements from individual small biological model organisms such as C. elegans or isolated single cells have been limited by poor sensitivity of existing techniques and difficulties in resolving very small heat outputs. Here, by careful thermal engineering, we developed a robust, highly sensitive and bio-compatible calorimetric platform that...

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PMID: 32532993
DOI: 10.1038/s41467-020-16690-y
PMCID: PMC7293274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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