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Article

Bridging the phenotypic gap: real-time assessment of mitochondrial function and metabolism of the nematode Caenorhabditis elegans.

BMC physiology - 2 Apr 2008

Lagido Cristina, Pettitt Jonathan, Flett Aileen, Glover L Anne

Abstract excerpt

BACKGROUND: The ATP levels of an organism are an important physiological parameter that is affected by genetic make up, ageing, stress and disease. RESULTS: We have generated luminescent C. elegans through ubiquitous, constitutive expression of firefly luciferase, widely used for in vitro ATP determination. We hypothesise that whole animal luminescence reflects its intracellular ATP levels in vivo. To test this,...

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Identifiers

PMID: 18384668
DOI: 10.1186/1472-6793-8-7
PMCID: PMC2364618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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