Article
Longitudinal imaging of Caenorhabditis elegans in a microfabricated device reveals variation in behavioral decline during aging.
eLife - 31 May 2017
Churgin Matthew A, Jung Sang-Kyu, Yu Chih-Chieh, Chen Xiangmei, Raizen David M, Fang-Yen Christopher
Abstract excerpt
The roundworm C. elegans is a mainstay of aging research due to its short lifespan and easily manipulable genetics. Current, widely used methods for long-term measurement of C. elegans are limited by low throughput and the difficulty of performing longitudinal monitoring of aging phenotypes. Here we describe the WorMotel, a microfabricated device for long-term cultivation and automated longitudinal imaging of...
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