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Longitudinal imaging of Caenorhabditis elegans in a microfabricated device reveals variation in behavioral decline during aging.

eLife - 31 May 2017

Churgin Matthew A, Jung Sang-Kyu, Yu Chih-Chieh, Chen Xiangmei, Raizen David M, Fang-Yen Christopher

Abstract excerpt

The roundworm C. elegans is a mainstay of aging research due to its short lifespan and easily manipulable genetics. Current, widely used methods for long-term measurement of C. elegans are limited by low throughput and the difficulty of performing longitudinal monitoring of aging phenotypes. Here we describe the WorMotel, a microfabricated device for long-term cultivation and automated longitudinal imaging of...

Topics

Aging
Animals
Behavior, Animal
Caenorhabditis elegans
Longitudinal Studies
Optical Imaging
Parasitology
Phenotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28537553
DOI: 10.7554/eLife.26652
PMCID: PMC5484621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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