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Fatty acid β-oxidation is required for the differentiation of larval hematopoietic progenitors in Drosophila

12 Jun 2020

Abstract excerpt

Cell-intrinsic and extrinsic signals regulate the state and fate of stem and progenitor cells. Recent advances in metabolomics illustrate that various metabolic pathways are also important in regulating stem cell fate. However, our understanding of the metabolic control of the state and fate of progenitor cells is in its infancy. Using Drosophila hematopoietic organ: lymph gland, we demonstrate that Fatty Acid...

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PMID: 32530419
DOI: 10.7554/elife.53247

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