Article
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation.
Nature - 24 Sept 2009
Owusu-Ansah Edward, Banerjee Utpal
Abstract excerpt
Reactive oxygen species (ROS), produced during various electron transfer reactions in vivo, are generally considered to be deleterious to cells. In the mammalian haematopoietic system, haematopoietic stem cells contain low levels of ROS. However, unexpectedly, the common myeloid progenitors (CMPs) produce significantly increased levels of ROS(2). The functional significance of this difference in ROS level in the...
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