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Article

Lactate and glycerol-3-phosphate metabolism cooperatively regulate growth and redox balance during <i>Drosophila melanogaster</i> larval development

2019-01-10

Abstract excerpt

<h4>ABSTRACT</h4> The dramatic growth that occurs during Drosophila larval development requires rapid conversion of nutrients into biomass. Many larval tissues respond to these biosynthetic demands by increasing carbohydrate metabolism and lactate dehydrogenase (dLDH) activity. The resulting metabolic program is ideally suited to synthesize macromolecules and mimics the manner by which cancer cells rely on aerob...

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Literature Corpus work
3d85d7de-4b97-5fa1-9921-284fa3260be8
DOI
10.1101/517532
Open publication

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