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Article

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

Developmental cell - 27 Feb 2017

Bulusu Vinay, Prior Nicole, Snaebjornsson Marteinn T, Kuehne Andreas, Sonnen Katharina F, Kress Jana, Stein Frank, Schultz Carsten, Sauer Uwe, Aulehla Alexander

Abstract excerpt

How metabolism is rewired during embryonic development is still largely unknown, as it remains a major technical challenge to resolve metabolic activities or metabolite levels with spatiotemporal resolution. Here, we investigated metabolic changes during development of organogenesis-stage mouse embryos, focusing on the presomitic mesoderm (PSM). We measured glycolytic labeling kinetics from 13C-glucose tracing...

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Identifiers

PMID: 28245920
DOI: 10.1016/j.devcel.2017.01.015
PMCID: PMC5337618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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