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Article

Loss of RBF1 changes glutamine catabolism.

Genes & development - 15 Jan 2013

Nicolay Brandon N, Gameiro Paulo A, Tschöp Katrin, Korenjak Michael, Heilmann Andreas M, Asara John M, Stephanopoulos Gregory, Iliopoulos Othon, Dyson Nicholas J

Abstract excerpt

Inactivation of the retinoblastoma tumor suppressor (pRB) alters the expression of a myriad of genes. To understand the altered cellular environment that these changes create, we took advantage of the Drosophila model system and used targeted liquid chromatography tandem mass spectrometry (LC-MS/MS) to profile the metabolic changes that occur when RBF1, the fly ortholog of pRB, is removed. We show that...

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Identifiers

PMID: 23322302
DOI: 10.1101/gad.206227.112
PMCID: PMC3566311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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