Article
A fast and reliable method for detecting SNP rs67384697 (Hsa-miR-148a binding site) by a single run of allele-specific real-time PCR.
HLA - 1 Sept 2020
Malnati Mauro S, Biswas Priscilla, Ugolotti Elisabetta, Di Marco Eddi, Sironi Francesca, Parolini Francesca, Garbarino Lucia, Mazzocco Michela, Zipeto Donato, Biassoni Roberto
Abstract excerpt
Surface expression of human leukocyte antigen (HLA)-class I molecules is critical for modulating T/natural killer lymphocytes' effector functions. Among HLA molecules, HLA-C, the most recently evolved form of class I antigens, is subjected to both transcriptional and multiple post-transcriptional regulation mechanisms affecting its cell surface expression. Among the latter a region placed in the 3' untranslated...
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