Article
Rapid high-resolution melting method to identify human leukocyte antigen-G (HLA-G) 3' untranslated region polymorphism +3142C/G (rs1063320).
Molecular genetics & genomic medicine - 1 Nov 2021
Ben Salah Hamza, Jelassi Refka, Zidi Ines, Ben Amor Amor, Bizid Sondes, Ammi Radhia, Guizani Lamia, Bouratbine Aida, Aoun Karim, Chelbi Hanen
Abstract excerpt
BACKGROUND: HLA-G is a non-classical class I gene of the human Major Histocompatibility encoding molecules with immune-modulatory properties. Expression of HLA-G is being largely studied in pathological conditions, such as tumors, viral infections, inflammation, and autoimmune diseases, grafted tissues, among others. HLA-G +3142C/G (rs1063320: dbSNP database) polymorphism is located in 3' UTR of HAL-G and plays a...
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