Article
An accurate and reliable real time SNP genotyping assay for the HLA-G +3142 bp C>G polymorphism.
Tissue antigens - 1 Sept 2012
Bortolotti D, Gentili V, Melchiorri L, Rotola A, Rizzo R
Abstract excerpt
Human leukocyte antigen (HLA)-G is a non classical HLA class I antigen with immuno-modulatory functions. The HLA-G gene is characterized by a +3142C>G variant in the 3' untranslated region which is suggested to control protein production and to be associated with pathological conditions. DNAs form 221 randomly selected healthy subjects were genotyped for HLA-G +3142C>G polymorphism by polymerase chain...
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