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Article

Simple methods for the detection of HLA-G variants in coding and non-coding regions.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Nückel Holger, Castelli Erick C, Moreau Philippe, Ochsenfarth Crista, Horn Peter A, Rebmann Vera

Abstract excerpt

The non-classical human leukocyte antigen (HLA)-G plays a crucial role in the induction of tolerance at the feto-maternal interface as well as in transplantation, cancer, inflammation, and autoimmune diseases. To understand gene regulation and the impact of polymorphic sites on the function, simple and easy feasible approaches are needed for the detection of HLA-G variants in coding and non-coding regions. Here...

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PMID: 22665231
DOI: 10.1007/978-1-61779-842-9_7

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