Article
Myeloid-Derived Suppressor Cells in the Context of Allogeneic Hematopoietic Stem Cell Transplantation.
Frontiers in immunology - 1 Jan 2020
D'Aveni Maud, Notarantonio Anne B, Bertrand Allan, Boulangé Laura, Pochon Cécile, Rubio Marie T
Abstract excerpt
Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the capacity to suppress adaptive immune responses. In the context of allogeneic hematopoietic stem cell transplantation (allo-HSCT), MDSCs (in the donor graft and in the recipient, after allo-HSCT) might mediate immune suppression through multiple mechanisms. However, it remains unclear how MDSCs can be distinguished from their normal...
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