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Article

The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells.

Biomolecules - 9 Jun 2020

Butera Giovanna, Brandi Jessica, Cavallini Chiara, Scarpa Aldo, Lawlor Rita T, Scupoli Maria Teresa, Marengo Emílio, Cecconi Daniela, Manfredi Marcello, Donadelli Massimo

Abstract excerpt

The cancer secretome is a rich repository of useful information for both cancer biology and clinical oncology. A better understanding of cancer secretome is particularly relevant for pancreatic ductal adenocarcinoma (PDAC), whose extremely high mortality rate is mainly due to early metastasis, resistance to conventional treatments, lack of recognizable symptoms, and assays for early detection. TP53 gene is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32526853
DOI: 10.3390/biom10060884
PMCID: PMC7356389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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