Article

SWATH-MS based proteomic profiling of Pancreatic Ductal Adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways

2020-06-05

Abstract excerpt

Pancreatic cancer accounts for 2.8% of new cancer cases worldwide and is projected to become the second leading cause of cancer-related deaths by 2030. Patients of African ancestry appear to be at an increased risk for pancreatic ductal adenocarcinoma (PDAC), with worse severity and outcomes. The purpose of this study was to map the proteomic and genomic landscape of a cohort of PDAC patients of African ancestry....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 46f31f1c-ffbd-5be5-b830-bf28c807f6bb
DOI: 10.1101/2020.06.04.20116640

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SWATH-MS based proteomic profiling of Pancreatic Ductal Adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathwaysDOI 10.1101/2020.06.04.20116640Read

SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways.Semantic proximity Read

Mass spectrometry-based proteomic analysis of PDAC samplesSemantic proximity Read

Proteogenomic analysis of pancreatic cancer subtypes.Semantic proximity Read

Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinomaSemantic proximity Read

Proteogenomic Analysis of Pancreatic Cancer SubtypesSemantic proximity Read

Targeted and Explorative Profiling of Kallikrein Proteases and Global Proteome Biology of Pancreatic Ductal Adenocarcinoma, Chronic Pancreatitis, and Normal Pancreas Highlights Disease-Specific Proteome RemodellingSemantic proximity Read

Integrated proteomics and phosphoproteomics reveal perturbed regulative pathways in pancreatic ductal adenocarcinomaSemantic proximity Read

Machine Learning and Network Analyses Reveal Disease Subtypes of Pancreatic Cancer and their Molecular CharacteristicsSemantic proximity Read

Proteome alterations in pancreatic ductal adenocarcinoma.Semantic proximity Read

Proteomic and genomic profiling of pancreatic cancerSemantic proximity Read

Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cellsSemantic proximity Read

Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinomaSemantic proximity Read