Article
Dissection of the Role of CCM Genes in Tubulogenesis Using the Drosophila Tracheal System as a Model.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Schweizer Burguete Alondra B, Ghabrial Amin S
Abstract excerpt
Embryos deficient for an essential gene may show complex phenotypes that reflect pleiotropic functions and non-cell-autonomous requirements for the encoded protein. The generation of mosaic animals, where most cells are wild type, but a few cells are mutant, is a powerful tool permitting the detailed analysis of the cell autonomous function of a gene, in a particular cell type, at cellular and subcellular...
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