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Article

The Role of Estrogen Receptor-β in Breast Cancer

1 Jan 2012

Abstract excerpt

The discovery of a second estrogen receptor (ER), ERβ, has led to a reevaluation of estrogen action. The widespread expression of ERβ-like proteins in normal and neoplastic mammary tissues suggests a role of ERβ in the breast. Little progress has been made in elucidating this role or roles, but the presence of two ERs and variant isoforms in breast cancers presents challenges and opportunities to tease out...

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PMID: 22271289
DOI: 10.1055/s-0031-1299592

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