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Estrogen Receptor Signaling in Breast Cancer

23 Sept 2023

Abstract excerpt

Estrogen receptor (ER) signaling is a critical regulator of cell proliferation, differentiation, and survival in breast cancer (BC) and other hormone-sensitive cancers. In this review, we explore the mechanism of ER-dependent downstream signaling in BC and the role of estrogens as growth factors necessary for cancer invasion and dissemination. The significance of the clinical implications of ER signaling in BC,...

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PMID: 37835383
DOI: 10.3390/cancers15194689

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