Article
Transgenerational stability of the Arabidopsis epigenome is coordinated by CG methylation.
Cell - 7 Sept 2007
Mathieu Olivier, Reinders Jon, Caikovski Marian, Smathajitt Chotika, Paszkowski Jerzy
Abstract excerpt
Maintenance of CG methylation ((m)CG) patterns is essential for chromatin-mediated epigenetic regulation of transcription in plants and mammals. However, functional links between (m)CG and other epigenetic mechanisms in vivo remain obscure. Using successive generations of an Arabidopsis thaliana mutant deficient in maintaining (m)CG, we find that (m)CG loss triggers genome-wide activation of alternative...
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