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Article

Loss of myocyte enhancer factor 2 expression in osteoclasts leads to opposing skeletal phenotypes.

Bone - 1 Sept 2020

Blixt Nicholas, Norton Andrew, Zhang Anqi, Aparicio Conrado, Prasad Hari, Gopalakrishnan Rajaram, Jensen Eric D, Mansky Kim C

Abstract excerpt

Osteoclasts are multinuclear cells that resorb bone. Osteoclast differentiation is regulated by multiple transcription factors which may be acting in a single or multiple factor complex to regulate gene expression. Myocyte enhancer factor 2 (MEF2) is a family of transcription factors whose role during osteoclast differentiation has not been well characterized. Because MEF2A and MEF2D are the family members most...

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Identifiers

PMID: 32512162
DOI: 10.1016/j.bone.2020.115466
PMCID: PMC7443313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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